Back to high school bio: What is DNA? And why is it so important now for your future health?
To understand DNA, let's first consider an analogy. Think of your body as a computer. Software is composed of 1's and 0's that tells the computer what to do (such as open an awesome blog). The computer reads the software and the hardware executes the encoded actions.
Similarly, DNA is composed of four letters (A, T, C, G) that tells your cells what to do. DNA is the software for building and maintaining your brain and body. Your cells are mini computer chips that carry out the DNA's instructions.
Certain DNA instructions are grouped together. These groups are called genes, and they are responsible for certain traits. These genes have largely influenced your height, eye color, skin complexion, and even attractiveness level.
Now imagine you could change or rewrite your DNA or genes. Yes, you could cure diseases like diabetes, but you could also create designer babies or the smartest race on Earth.
When it comes to DNA, there are two main steps. First, you need to read or sequence the letters. Next, you need to write, or synthesize the new DNA that you want to insert.
Image Credit: Singularity Hub |
Why is this such a big deal? First, you could figure out all the "health genes" by sequencing 100 of the oldest, healthiest people on the planet.
But reading is just the beginning. We are working on gene therapy which promises the ability to change our genes. Doctors could replace our genes with these "health genes" to provide a longer, healthier life. Furthermore, gene therapy could be used to treat a range of diseases such as AIDS, obesity, Alzheimer's, and cancer.
Gene therapy also poses many ethical questions. What if we went beyond disease? We could change our skin color, athletic ability, attractiveness, and even our own intelligence. We may not do this ourselves, but our neighbors are bound to do it to their children to get the competitive advantage.
Here are some of my thoughts on how gene therapy could affect different careers:
- Politician -- Social Intelligence genes
- Pro Pianist -- Perfect Pitch genes, fine-muscle coordination genes.
- Pro Football -- Eyesight enhancing genes, muscle enhancer genes.
- NSA & CIA -- Intelligence genes
- Translators -- Language (Broca's Area) genes
© Nicholas Shah and Learning More Than Living, 2013. Please note that the material included this was not written by a licensed medical professional. Therefore, please consult your physician before trying anything suggested in this article. Please note that there was an image used from Singularity Hub. This blog does not claim ownership of that image. Nicholas Shah does not claim ownership to the ideas put forth in this article. Unauthorized use and/or duplication of this material without express and written permission from this blog’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Nicholas Shah and Learning More Than Living with appropriate and specific direction to the original content. Thank You.
Something to think about for each nucleic acid normally found in human DNA...
ReplyDeleteA. A gene goes from DNA → RNA → Protein. This central dogma of genetics appears nowhere in this article, and many of the traits you listed (such as intelligence) are polygenetic with complex regulatory mechanisms that matter just as much, or more, than the genes which will also rely heavily on environmental factors for the actual phenotype of any individual.
T. 97.2% of the DNA in the Human genome are not in genes. You seem to have an obsession with coding sequences.
http://www.nature.com/nrg/journal/v11/n8/fig_tab/nrg2814_T2.html
C. There are many serious risks involved in gene therapy. People have died from multiple organ system failure due to the immune response to the viruses given as vectors to deliver new genes. http://www.mayoclinic.com/health/gene-therapy/MY00105/DSECTION=risks
G. Professional musicians and athletes are more dependent on rigorous practice schedules than on genetics. According to you, translators will be replaced by computers. I really hope "NSA & CIA -- Intelligence genes" was a pun. Finally, anyone with a reasonable amount of social intelligence wouldn't be a politician.
Transcribing your comment…
ReplyDeleteU. This article is focusing on the exciting changes that may arrive soon and assumes you know the basics.
A. The proteins made give function to whatever it is you are trying to manipulate. It is implied controlling expression of the coding regions will be useful as well.
G. Everything has risks. Safety will improve as this technology advances.
C. Genetics plays an important role in predisposing these professions…
-ARGotI